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Insulin Action

There are several types of insulin. They are classified by how long they act and are generally referred to as  rapid-acting, short-acting, intermediate and long-acting. Each type of insulin has a certain time period in which it works.  In order to understand insulin action more completely, it is helpful to know the onset, peak, and duration of the insulin you take.

  • Onset refers to when the insulin starts to work.
  • Peak refers to when the insulin is working its hardest.
  • Duration refers to how long the insulin works.

The chart below describes the insulin action of the the types of insulin most commonly used in treating diabetes.

Types of insulin

 

 

Onset

Peak

Effective Duration

Rapid-acting

 aspart (Novolog)

 lispro (Humalog)

 glulisine (Apidra)

10 to 30 minutes

½  to 3 hours

3 to 5 hours

Short-acting

Regular

 

30 – 60 minutes

1 to 5 hours

8 hours

Intermediate-acting

NPH

 

1 to 4 hours

 

 

4 to 12 hours

 

 

 

14 to 26 hours

Long-acting, peakless

glargine (Lantus)

 

 

 

 

1 to 2 hours

 

 

Flat, basal-like

 

 

24 hours

 


 

 

 

 

  

 

 

 

 

 

 

 

For more information, you may want to purchase our book What You Need to Know About Diabetes - A Short Guide, which can be ordered online.

 
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